RT Journal Article
SR Electronic
T1 The six-minute walking test in patients with severe COPD: What conditions are matters?
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P2901
VO 40
IS Suppl 56
A1 Maria Sanzharovskaya
A1 Anna Fisenko
A1 Georgy Chernogoryuk
A1 Konstantin Zavadovskiy
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P2901.abstract
AB The distance walked during a Six-Minute Walk Test (6 MWD) is used for following the natural history of COPD, for assessing the response to therapeutic interventions, to estimate the prognosis in BODE index, in cardiology it is used to estimation of the chronic heart failure. Normally patients with COPD III and IV stage are patients with polypatology.Aim: to investigate the pathologic conditions which influence on the 6 MWD in severe COPD patents with and without exacerbation.Methods: 120 patients were clinically and functionally investigated in the study during and after hospitalization in the pulmonology department. Additionally for 16 patients was performed gated blood pool single photon emission computer tomography (gbSPECT) and proBNP measurement.Results: View this table:Conclusion: in patients with COPD during disease exacerbation the main 6MWD limiting factors are respiratory function failure, hypoxia and muscle dysfunction. In stable state left and right heart dysfunction even without clinically significant heart failure contribute to 6MWD limitation.