RT Journal Article SR Electronic T1 Perioperative considerations for patients with asthma underwent thoracic surgery JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P4420 VO 40 IS Suppl 56 A1 Yordanka Yamakova A1 Rosen Petkov A1 Georgi Yankov A1 Danail Petrov YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P4420.abstract AB Asthmatic patients are a challenging population for anesthesiologists.The aim of this study was to determine the perioperative complications in asthmatic patients with symptoms before the surgery.Material and metods: From 2007 to 2011 44 patients with asthma underwent thoracotomy. We classified the patients into two groups: First group (n 19) - patients with asthma who currently have no symptoms and second group (n 25) - asthmatic patients with symptoms before surgery. Pulmonary function was optimized preoperatively in all patients and airway obstruction was controlled by using steroids and bronchodilators. We conducted deep anesthesia with Sevoflurane, Fentanyl and Pipecuronium. We monitored several parameters: tidal volume, inspiratory, expiratory volume, Ppeak, Pplat, ETCO2, PaC02.Results: The First group patients had less incidences of perioperative bronchospasm than those in the second (p<0.025). We detected some statistical differences in the parameters: the gradient between ETCO2, PaC02 is bigger in second group (p<0.025) and we detected an increasing Ppeak and Pplat in asthmatic patients with symptoms before surgery.Conclusion: Symptomatic asthmatic patients had more the incidence rate of the perioperative complications. With deepening anesthesia level and aggressive pharmacological management the anesthesiologist minimize the risk of complications.