%0 Journal Article %A Valeria Lollobrigida %A Anna Maria Zicari %A Azzurra Cesoni Marcelli %A Paola Pansa %A Giovanni Ragusa %A Lucia Leonardi %A Giancarlo Tancredi %A Marzia Duse %T Effects of obesity on lung function and SaO2 in children with habitual snoring %D 2012 %J European Respiratory Journal %P P3845 %V 40 %N Suppl 56 %X BACKGROUND: Habitual Snoring (HS) is a common pediatric condition with a prevalence ranged between 7 and 10 %. It has a multifactorial etiology and it is often associated with several comorbilities. Many studies showed low spirometric values in overweight and obese children, but the association with HS is still unclear.AIM: The purpose of this Study is to evaluate the relationship between obesity, lung function and nocturnal minimum oxygen saturation (SaO2) in a pediatric population with HS.METHODS: We enrolled 53 children (mean age 9,5, 34 male) in the Pediatric Department of Immunology and Allergology of Policlinico Umberto I in Rome. All patients were positive to a validated questionnaire for sleep disordered breathing, performed a spirometry and a nocturnal pulse oximetry. Percentile Body Mass Index (BMI) was calculated for each patient.The selected patients were divided into 4 percentile BMI groups (Group I: percentile 0-25, group II: percentile 26-50, group III: percentile 51-75, group IV: percentile 76-100).RESULTS: We found that group IV (BMI>75th percentile) had significantly lower values of SaO2 and forced expiratory volume in one second (FEV1) when compared with the other groups (respectively p<0,02 and p<0, 05).CONCLUSIONS:Lung function (reduced FEV1) and minimum SaO2 areinfluenced by the progressive increase in percentile BMI with changes in FEV1 better demonstrated when BMI >75th percentile. Our findings suggest that in children with HS, the presence of obesity can cause a sistemic inflammatory pattern that negatively influence lung function and blood SaO. %U https://erj.ersjournals.com/content/erj/40/Suppl_56/P3845.full.pdf