@article {ChushkinP2614, author = {Mikhail Chushkin and Valentina Aksenova and Elena Bogorodskaya and Vadim Koroev and Sergey Mandrykin and Dmitriy Zhutikov and Eduard Tikhokhod and Sergey Smerdin}, title = {The factors associated to pulmonary impairment in patients with treated tuberculosis}, volume = {40}, number = {Suppl 56}, elocation-id = {P2614}, year = {2012}, publisher = {European Respiratory Society}, abstract = {Tuberculosis is associated with frequent pulmonary impairment. Low lung function is an independent predictor of all-cause or respiratory disease mortality. The aim of the study was to ascertain the factors affecting lung function in patients treated for pulmonary tuberculosis.Methods: In 302 patients who were treated for pulmonary tuberculosis (188 men and 114 women between the ages of 20 and 82 years) and observed at local dispensaries pulmonary function tests were performed.Results: Out of 302 patients, 114 (37,8\%) had low lung function (FEV1 \< 80\% predicted). According to ATS/ERS criteria we classified 8,3\% of subjects as having mild impairment; 18,2\% of subjects as having moderate impairment; and 11,3\% of subjects as having severe impairment. Risk factors for low lung function were positive culture in the past (odds ratio [OR] 4.3; 95\% confidential interval [CI] 2.43 to 7.71; p\<0.001), age 40 or older (OR 2.73; 95\% CI 1.46 to 5.11; p= 0.002); recurrence of tuberculosis (OR 2.61; 95\% CI 1.38 to 4.91; p=0.004); education less than 15 yrs (OR 1.79; 95\% CI 1.05 to 3.05; p\<0.05). We did not find influence of gender (males vs females, OR 1.36; 95\% CI 0.84 to 2.21; p\>0.05); smoking ever vs never (OR 1.21; 95\% CI 0.74 to 1.97; p\>0.05).Conclusion: Risk factors for low lung function were culture-positive pulmonary tuberculosis in the past, age more than 40 years, recurrence of tuberculosis which may increase the prevalence of low lung function in the patients treated for pulmonary tuberculosis.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/40/Suppl_56/P2614}, eprint = {https://erj.ersjournals.com/content/40/Suppl_56/P2614.full.pdf}, journal = {European Respiratory Journal} }