PT - JOURNAL ARTICLE AU - Milic Medenica AU - Redzep Kraja AU - Miras Medenica TI - Pleural effusions in lung cancer DP - 2012 Sep 01 TA - European Respiratory Journal PG - P1267 VI - 40 IP - Suppl 56 4099 - http://erj.ersjournals.com/content/40/Suppl_56/P1267.short 4100 - http://erj.ersjournals.com/content/40/Suppl_56/P1267.full SO - Eur Respir J2012 Sep 01; 40 AB - The most common cause of malignant effusions in males is lung cancer. Malignant effusions are the result of spread of lung cancer to pleura or dissemination of metastatic tumour to one of the pleural surfaces. Paramalignant effusions are the result of lung cancer, but not a result of spread of malignant diseases to pleura.Methods: The study group comprised of patients in territory of Montenegro, in time period from 01.01.2008 to 31.07.2011. All patients with pleural effusions had their pleural liquid citologically tested, and histological processing of samples of pleural tissue obtained by blind needle biopsy (66 patients) or VATS (8 patients) was done. Descriptive statistical method and retrospective study were used.Results: Total number of newly diagnosed cases of lung cancer was 585 (squamous cell ca - 361 (62%); SCLC- 139 (23.5%) adenoca 85– (14.5%)). Paramalignant effusion was diagnosed in 33 patients (5.64%). Paramalignant effusion was found in 17 patients with squamous cell ca (4.7%), in 9 patients with SCLC (6.5%) and in 3 patients with adenoca (3.6%). No statistical significance was found when correlating frequency of paramalignant effusion to hystological type of lung cancer (p>0.05). Malignant effusion was diagnosed in 55 patients. Malignant effusion was the most common in pts suffering from adenoca (found in 26 patients – 30.6%, p<0.01), while malignant effusions were found in 13 pts with squamous cell ca (3.6%), and in SCLC in 9 patients (6.5%).Discussion: No statistical significance was found when trying to correlate frequency of paramalignant effusion in different histological types of lung cancer. In the group of patients with malignant effusion adenoca is the most common causal factor of spread of malignant disease to pleura.