RT Journal Article SR Electronic T1 Prognosis of patients with active tuberculosis requiring intensive care unit JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P1995 VO 40 IS Suppl 56 A1 Filiz Kosar A1 Levent Dalar A1 Emel Eryüksel A1 Sibel Yurt YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P1995.abstract AB Tuberculosis remains an important health problem. The aim of this sudy to determine the mortality rate of patients with active tuberculosis requiring intensive care unit.We conducted an observational study. Patients with confirmed active tuberculosis admitted to ICU between May 2010 and January 2012 were identified and enrolled. Clinical data and mortality rate were recorded.A total of 19 tuberculosis patients admitted to ICU were included. Mean Acute Physiology and Chronic Health Evaluation (APACHE) II score at admission was 17.00 ±7,7. Twelve patients (63 %) required mechanical ventilation. The mortality was 12 of 19 (63 %). The reasons associated with ICU admission were massive hemoptysis in two patients, empyema in one patients, active tuberculosis and sepsis in nine patients, tuberculous meningitis in one patients and tuberculosisand/or pneumonitis in others. High APACHE II score and invasive mechanical ventilation use were significiantly associated mortality (p<0.005 ve p<0.004, r = -0.74)These data indicate a high mortality of patients with tuberculosis requiring intensive care unit care and further studies needed to determine associated risk factors.Keywords: mortality, tuberculosis, intensive care.