%0 Journal Article %A Olena Semendyayeva %A Nadiya Monogarova %A Vladimyr Gavrisyk %A Evgeniya Merenkova %A Sergey Leshenko %T Surgical lung biopsy - Gold standard for diagnosis of idiopathic interstitial pneumonia? %D 2012 %J European Respiratory Journal %P P3484 %V 40 %N Suppl 56 %X The current classification of idiopathic interstitial pneumonia (IIP) is based on the account of the specificities of the clinical picture, radiological and pathological features. This raises the question of how much the necessity of verification of the diagnosis of IIP data pathologic study biopsy or autopsy lung material. To answer this question, we asked three highly-skilled pathologist with considerable experience in pulmonology, to conduct an independent analysis of the same histological lung tissue of patients with various forms of IIP. For the analysis of slides, presented 73 patients with IIP. Material for histological study was obtained during open and videotorakoskopic lung biopsy and at autopsy.According to clinical studies and results of computed tomography high-resolution was found clinical diagnosis of idiopathic fibrosing alveolitis (IFA) for the pathomorphological study, nonspecific interstitial pneumonia (NSIP), lymphoid interstitial pneumonia (LIP), cryptogenic organizing pneumonia (COP) and respiratory bronchiolitis associated with interstitial lung disease (RB-ILD). Match the clinical diagnosis with the conclusions of three experts were only in 15 cases (20.5%), two experts in 35 (47.9%) and one - in 15 cases (20.5%). In most cases, differences in interpretation of histological data did not go beyond the group of IIP. Differentiated forms of IIP in practice pulmonology very difficult. At the same time, identification of each form of IIP is not an end in itself, it is essential if accurate diagnosis determines the treatment tactics. In our opinion, surgical biopsy of the lungs is necessary in the differential diagnosis of IIP with other interstitial lung diseases. %U https://erj.ersjournals.com/content/erj/40/Suppl_56/P3484.full.pdf