TY - JOUR T1 - No more bets? FEV1, DLCO or exercise test - What is essential in the qualifying of patients with lung cancer for surgery? JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P461 AU - Monika Franczuk AU - Stefan Wesolowski AU - Piotr Rudzinski AU - Jerzy Usiekniewicz AU - Marek Kram AU - Tadeusz Orlowski Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P461.abstract N2 - According to current recommendations (ERS/ESTS 2009) lung function testing and assessment of exercise tolerance are helpful in estimation of patients eligibility for surgery and risk stratification of postoperative complications. Nevertheless the validity and cut-off values are still being discussed.The aim of the study was to analyze the lung function (FEV1, DLCO) and six-minute walk test (6MWT) in patients operated on due to lung cancer in terms of postoperative complications. The analysis embraced 162 pts (age 63,5±8,3 yrs, 100 M), with no history of previous lung resection, chemotherapy or radiotherapy within the chest. Postoperative complications were observed in 54 patients (32,9%), more frequently in male (39 vs 24%), in pts over 65 yrs (38 vs 28%) and in airway obstruction (48 vs 22%). These patients were older (66,7 vs 63,5 yrs p<0,02), had lower baseline FEV1 (74,1 vs 89,8% p<0,0001), ppoFEV1 (57,5 vs 70,7% p<0,0001) and ppoDLCO (49,6 vs 55,6%, p<0,05), similar walking distance in 6MWT (411 vs 432 m, ns) with lower SaO2 (95,8 vs 96,9%, p<0,0001) and deeper drops of SaO2 during exercise (3,0 vs 2,1%, p<0,05). Univariate analysis showed that baseline FEV1, ppoFEV1, baseline and minimal saturation during 6MWT were significant for postoperative complications. ROC analysis revealed FEV1, ppoFEV1 and SaO2 during 6MWT as statistically significant prognostic variables. Such a significance was not found for age, baseline DLCO and walking distance in 6MWT.Conclusions: Impairment of lung function described by FEV1 and desaturation caused by 6MWT appeared to be prognostic for postoperative complication in lung cancer patients who underwent surgical treatment. ER -