RT Journal Article
SR Electronic
T1 Refractory asthma in elderly patients in the UK
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P772
VO 42
IS Suppl 57
A1 Rekha Chaudhuri
A1 Charles McSharry
A1 Liam Heaney
A1 Robert Niven
A1 Christopher Brightling
A1 Andrew Menzies-Gow
A1 Christine Bucknall
A1 Adel Mansur
A1 Wai-Ting Nicola Lee
A1 Malcolm Shepherd
A1 Mark Spears
A1 Neil Thomson
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P772.abstract
AB BACKGROUNDSevere refractory asthma affects all age-groups including the elderly. We examined the effect of age on clinical and inflammatory outcomes in patients recruited to the British Thoracic Society [BTS] Severe Asthma Registry.METHODSAll subjects with refractory asthma [ATS criteria] ≥18 years old from the BTS Severe Asthma Registry were included in the analysis.RESULTS754 subjects with refractory asthma were studied. Age was normally distributed (mean of 49.4 yrs [SD 13.6], range 18-82 yrs). Age correlated with a lower number of unscheduled emergency visits [-0.137; p=0.000], hospital admissions [r = -0.147; p=0.000], ITU admissions [r = -0.095; p=0.010], but asthma control was not affected [ACQ or ACT scores]. FEV1 % predicted was lower with increasing age. Comparison of clinical and inflammatory outcomes in patients aged <65 years with those aged ≥65 years is shown in the table.View this table:CONCLUSIONElderly patients with refractory asthma have poor symptom control and asthma quality of life, at levels similar to younger patients with refractory asthma. However, the number of severe exacerbations and unscheduled emergency visits is slightly less in the elderly group.