TY - JOUR T1 - Bronchoalveolar lavage cytology resembles sarcoidosis in a subgroup of granulomatous CVID JF - European Respiratory Journal JO - Eur Respir J SP - 922 LP - 924 DO - 10.1183/09031936.00025513 VL - 43 IS - 3 AU - Florian Kollert AU - Nils Venhoff AU - Sigune Goldacker AU - Claudia Wehr AU - Niklas Lützen AU - Reinhard E. Voll AU - Antje Prasse AU - Klaus Warnatz Y1 - 2014/03/01 UR - http://erj.ersjournals.com/content/43/3/922.abstract N2 - To the Editor:We read with great interest the article by Bouvry et al. [1] regarding similarities and differences between interstitial lung disease (ILD) in granulomatous common variable immunodeficiency (CVID) and sarcoidosis. In this retrospective study, differential bronchoalveolar lavage (BAL) cytology was analysed in 14 patients with granulomatous CVID and ILD. The authors found BAL lymphocytosis (>20%) in 11 out of 14 patients and a mean±sd proportion of BAL lymphocytes of 37.3±15.3%. Unlike the sarcoidosis group (5.3±4.0), the CD4/CD8 ratio was low in the analysed patients with granulomatous CVID and ILD (1.6±1.1, n=10) and even <1 in half of the patients (n=5). Bouvry et al. [1] concluded that there are significant differences in differential BAL cytology between sarcoidosis and granulomatous CVID.We therefore retrospectively analysed a subgroup of 11 CVID patients (seven … ER -