TY - JOUR T1 - Waist-to-height ratio and lung function among adults. The PLATINO cohort JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P4717 AU - Ana Maria Menezes AU - Fernando Cesar Wehrmeister AU - Rogelio Perez-Padilla AU - Adriana Muino AU - Maria Victorina Lopez Varella AU - Gonzalo Valdivia AU - Carmem Lisboa AU - Jose R. Jardim AU - Carlos Talamo AU - Pedro C. Hallal AU - Maria Montes de Oca Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P4717.abstract N2 - Background: waist-to-height ratio (WtHR) has been used as a better indicator for obesity and fat distribution rather than body mass index or waist circumference and a possible risk for several chronic diseases, including respiratory impairment.Aim: to evaluate the association between changes in WtHR and lung function among adults.Methods: a follow-up was conducted in three out of the five centers of the PLATINO study: Montevideo, Santiago, and Sao Paulo, after a period of 5, 6 and 9 years, respectively. The same spirometers, questionnaires and standardized methods for measuring height and waist circumference implemented in the baseline were carried out in the follow-up. The main exposure variable was WtHR, being a cut-off point of ≥ 0.5 considered as an abdominal fat pattern; for the longitudinal analysis, this variable was categorized in four groups: low WtHR at both visits, high WtHR at the baseline, high WtHR at the follow-up visit and high WtHR at both visits. The outcomes were absolute FEV1 and FVC parameters. Unadjusted and adjusted linear regression models were performed to evaluate the association.Results: a reduced FEV1 was observed in the crude analysis (β = -0.23L – 95% CI -0.36; -0.10) for those subjects who had a high WtHR at both visits; in the adjusted analysis the statistical significance was lost (β = -0.04L – 95% CI -0.09; 0.02); for the FVC parameter, there was a reduction in the crude and adjusted analysis ((β = -0.11L – 95% CI -0.19; -0.03) for those subjects who had a high WtHR at both visits.Conclusion: it is suggested that the maintenance of a high waist-to-height ratio can be a predictor of low lung function, mainly FVC. ER -