TY - JOUR T1 - Multidimensional approach to non-cystic fibrosis bronchiectasis: the FACED score JF - European Respiratory Journal JO - Eur Respir J SP - 1357 LP - 1367 DO - 10.1183/09031936.00026313 VL - 43 IS - 5 AU - Miguel Á. Martínez-García AU - Javier de Gracia AU - Monserrat Vendrell Relat AU - Rosa-Maria Girón AU - Luis Máiz Carro AU - David de la Rosa Carrillo AU - Casilda Olveira Y1 - 2014/05/01 UR - http://erj.ersjournals.com/content/43/5/1357.abstract N2 - Bronchiectasis is a multidimensional disease and, therefore, its severity or prognosis cannot be adequately quantified by analysing one single variable. The objective of the present study was to develop a multidimensional score that classifies the severity of bronchiectasis according to its prognosis. This is an observational multicentre study including 819 patients diagnosed with non-cystic fibrosis bronchiectasis using high-resolution computed tomography. 397 subjects were selected at random to construct the score while the remaining 422 were used for its validation. The outcome was 5-year all-cause mortality after radiological diagnosis. A logistic regression analysis was used to select the variables included in the final score. The final seven-point score incorporated five dichotomised variables: forced expiratory volume in 1 s % predicted (F, cut-off 50%, maximum value 2 points); age (A, cut-off 70 years, maximum value 2 points); presence of chronic colonisation by Pseudomonas aeruginosa (C, dichotomic, maximum value 1 point); radiological extension (E, number of lobes affected, cut-off two lobes, maximum value 1 point); and dyspnoea (D, cut-off grade II on the Medical Research Council scale, maximum value 1 point) to construct the FACED score. The validation cohort confirmed the score’s validity. We conclude that this easy-to-use multidimensional grading system proved capable of accurately classifying the severity of bronchiectasis according to its prognosis. An easy-to-use multidimensional grading system accurately classifies bronchiectasis severity according to prognosis http://ow.ly/tW3xx ER -