PT - JOURNAL ARTICLE AU - David Coultas AU - Bradford Jackson AU - Minyong Uhm AU - Karan Singh AU - Sejong Bae TI - Inability to perform paced step-test and self-reported physical activity are useful measures of functional capacity among patients with COPD DP - 2013 Sep 01 TA - European Respiratory Journal PG - P3694 VI - 42 IP - Suppl 57 4099 - http://erj.ersjournals.com/content/42/Suppl_57/P3694.short 4100 - http://erj.ersjournals.com/content/42/Suppl_57/P3694.full SO - Eur Respir J2013 Sep 01; 42 AB - Background: Functional capacity among patients with COPD is traditionally assessed with walking tests. Step-tests and measures of physical activity (PA) offer alternative methods.Objectives: To examine the relationships between an externally paced step-test (PST), self-reported PA, health-related quality of life, and 6-minute walking (6MW) distance.Methods: Analysis of baseline data from patients enrolled in a clinical trial. A three minute PST was performed at 22 steps/minute. PA was assessed with the rapid assessment of PA (RAPA) questionnaire categorized as active, intermediate, or low. Other measures were Chronic Respiratory Questionnaire (CRQ), SF-12, and 6MW. Cox regression was used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for factors independently associated with completion of the PST.Results: Of 325 patients mean age (SD) was 69 (10) years, 51% female, 92% white. The PST was administered to 84% and only 24% were able to complete entire 3 minutes. There were multiple clinically and statistically significant differences between the completers (C) and non-completers (NC) (Table).View this table:Inability to complete the PST was lower among active/intermediate vs. low PA (OR 0.7, CI 0.5-0.9) adjusting for age, gender, BMI, smoking status, GOLD stage, BODE index, and CRQ.Conclusions: These results suggest that the PST and RAPA offer feasible and clinically relevant measures among patients with COPD.Funding: NIH R18 HL092955.