PT  - JOURNAL ARTICLE
AU  - Mark Gaides
AU  - C. Gauci
AU  - Sergei Bogomazov
TI  - Pectus excavatum, small lungs or small chest cavity?
DP  - 2012 Sep 01
TA  - European Respiratory Journal
PG  - 176
VI  - 40
IP  - Suppl 56
4099  - http://erj.ersjournals.com/content/40/Suppl_56/176.short
4100  - http://erj.ersjournals.com/content/40/Suppl_56/176.full
SO  - Eur Respir J2012 Sep 01; 40
AB  - INTRODUCTION. It is accepted that a pectus it is primary deformation of the chest. An alternative explanation is that the lung is underdeveloped and the small lung retracts the chest wall. According to this hypothesis, the small lung to chest volume ratio augment the negative intrapleural pressure thereby deforming the chest wall.With surgical correction of the supposed chest deformity the chest cavity volume is increased and these small lungs are stretched even more than they were stretched. This traumatizes the lungs, further impairs their function.Patient's studied: 27 patients with Pectus Excavatum without surgical correction and 5 patients after surgical correction of the chest.Methods: Body-plethysmography, Cardio-Pulmonary Exercise test, mathematical modeling.Results.View this table:Spirometric functions before and after surgical correctionView this table:Cardiac functions before and after surgical correctionDiscussion. The preoperative TLC and VC were almost normal, but FRC and RV was significantly increased in the 27 patients. Central hemodynamic parameters were also within normal limits. Hence, the chest deformity is a secondary effect caused by this "Little Lung Syndrome".After surgery, all lung volumes and hemodynamic functions decreased.Conclusion. It is probable that we need to change the surgical technique to not only correct the chest wall defect but also to reduce the intra-thoracic volume, so as not to stretch the lungs.