RT Journal Article SR Electronic T1 Socio-economic variation in health care access and quality of life in COPD; exploring the role of psychosocial factors JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P2384 VO 42 IS Suppl 57 A1 Sophia Georgopoulou A1 Helen Booth A1 Hannah Thornton A1 Alison Wright A1 John Weinman A1 Patrick White YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/P2384.abstract AB Background: Psychosocial factors such as illness perceptions, self-efficacy and social capital play a significant role in the management and quality of life of chronic diseases. We examined associations between psychosocial factors and socio-economic status, health care access and quality of life in COPD and to consider their role as possible mediators in these relationships.Method: Cross-sectional, interview-based survey in London of COPD patients >40 years recruited in primary care. Measures included socio-economic status (SES) indicators (weekly household income, educational attainment, occupational class and IMD scores), illness perceptions (IPs), quality of life (CRQ-SAS), MRC dyspnoea scale, general self-efficacy (GSE) scale, measures of social capital (SC), HAD scale, and lung function (spirometry). Mediation analysis was used to explore the mechanism of their relationships.Findings: 176 spirometry confirmed COPD participants. 38.6% female, mean age 69 years (range: 42-94). GOLD Grade 1=15%; 2=51%; 3=30%; 4=5%. The relationship between SES and HCA was not significantly mediated by any of the psychosocial variables examined. The association between SES (income level): and dyspnea (QoL) was mediated by identity consequences, feelings of trust and safety and value of life (effect=0.26, SE=0.09, [95% CI]=0.0804-0.4503). Similar associations were found between SES (income level) and fatigue, emotional function, self-efficacy, mastery, and depression.Consequences: Psychosocial variables were significantly associated with HCA and QOL in COPD but their role as mediators was of minor importance in the relationship between SES and HCA and QOL in COPD.