PT  - JOURNAL ARTICLE
AU  - Güzin Cinel
AU  - Nural Kiper
AU  - Diclehan Orhan
AU  - Ebru Yalçin
AU  - Deniz Dogru
AU  - Ugur Özçelik
AU  - Berna Oguz
AU  - Mithat Haliloglu
AU  - Gülsev Kale
TI  - Childhood diffuse parenchymal lung diseases: Diagnosis, treatment and outcome
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - P2350
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/P2350.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/P2350.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - Childhood diffuse parenchymal lung diseases are a group of heterogeneous disorders that have common histological features with a chronic course and associated with high morbidity and mortality.There is not an exact consensus about the terminology, classification, therapy and follow up of this disease because of its rarity and wide clinical spectrum.In this study, clinical features, laboratory, radiological and histopathological findings, therapy and outcome of 130 pediatric DPLDcases who were followed up at our hospital are retrospectively evaluated.We also tried to classify these patients according to the last classification scheme recommended.Our childhood DPLD series is the largest one in the literature that’s reported from a single center.Sixteen distinct disease groups are discussed under the DPLDtitle.Our patients’ mean age at diagnosis was 7,7years.The most frequent symptoms were cough and dyspnea in all disease groups.The diagnosis of patients were delayed between median 5,5months and 3years in all groups; and these patients were treated as if they had pneumonia, tuberculosis and asthma.As the presenting clinical manifestations are non-specific, every child, with a history of normal birth, who has signs and symptoms suggesting DPLD for more than 3months should be investigated in terms of DPLD. A group of patients with idiopathic interstitial pneumonia, idiopathic pulmonary hemosiderosis, pulmonary alveolar microlithiasis and diffuse chondroid malformation of the lung, could not be classified in the last classification scheme recommended by Children’s Interstitial Lung Disease(chILD) Network.These results indicate that a new classification system involving all these patients is required.