RT Journal Article
SR Electronic
T1 Cardiovascular events (CVE) in COPD patients
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P1871
VO 42
IS Suppl 57
A1 Sergey Avdeev
A1 Gulsara Baimakanova
A1 Alexander Chuchalin
YR 2013
UL http://erj.ersjournals.com/content/42/Suppl_57/P1871.abstract
AB Aim: To estimate the prevalence of CVE and compare the characteristics of patients with or without CVE during acute exacerbation of COPD (AECOPD).Methods: We analyzed the data from 80 patients (men 67, age 64,2 ± 7,8 yrs, BMI 25,8 ± 8,8 kg/m2) with AECOPD (history, clinical presentation, X-ray, pulmonary test, blood gases, serum levels of Heart-type fatty acid-binding proteins (H-FABP) and BNP-fragment).Results: CVE (acute myocardial infarction, pulmonary edema, a new arrhythmia, acute decompensation of chronic heart failure) were reported in 28(35%) patients with AECOPD on 3,8 ± 2,1 admission day. There were no differences between patients with or without CVE in demographics characteristics. We observed significant differences in the biomarkers levels, pulmonary tests, hypoxemia, echocardiographic parameters (Table 1).View this table:Table 1. Characteristics of patients with AECOPDConclusions: CVE may be more likely to occur in the setting of an AECOPD. Lung hyperinflation, hypoxemia, pulmonary hypertension, heart failure, mortality, increased levels of H-FABP, BNP-fragment were greater in AECOPD patients with CVE.