TY - JOUR T1 - Validity of the fractional exhaled nitric oxide (FE<sub>NO</sub>) for identification of bronchial hyperresponsiveness in a pulmonary function laboratory JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P1273 AU - Jorge Chancafe-Morgan AU - Yolanda Ramos-Quispe AU - Rosa Gomez-GarcĂ­a AU - Julio Vargas-Espinal AU - Luis Puente-MaestĂș Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P1273.abstract N2 - Objective: To evaluate the validity of the Fractional Exhaled Nitric Oxide test (FENO) for identification of bronchial hyperresponsiveness.Methods: We conducted a prospective, consecutive, observational study. Subjects who underwent a FENO and methacholine test (MT) for BH suspicion were included. The MT was the gold standard test. We assessed the cut-off point 35 ppb for a positive FENO result. We obtained the FENO sensitivity (S), specificity (E), positive predictive value (PPV) and negative predictive value (NPV). The data were analyzed with the SPSS 15 statistical program.Results: A total of 30 subjects were included. The mean age was 44,2 years (SD 16,7) and 10 (33 %) were male. The mean FENO value was 33,6 (SD 18,7). Of them, 12 (40%) had a positive MT and 12 (40%) a positive FENO result. The S, E, PPV and NPV were 75%, 83,3%, 75% and 83,3 %.Conclusions: According to our data, FENO seems to have a fairly good profile to predict MT results. ER -