@article {Ponneduthamkuzhyp4355, author = {Thomas James Ponneduthamkuzhy and B.R. Sandeep and P.V. Santhosh Kumar and Chetambath Ravindran}, title = {A study to analyse the clinical profile and outcome of hospitalised patients with H1N1 and the factors influencing the outcome}, volume = {38}, number = {Suppl 55}, elocation-id = {p4355}, year = {2011}, publisher = {European Respiratory Society}, abstract = {This was an observational study conducted in Institute of chest diseases, Calicut medical college,India between August 2009 and August 2010. All patients whose throat swabs were positive for H1N1 by Real time PCR and belonged to category C (severe disease)according to the clssafication by Ministry of health and family welfare were included in the study.Out of the 110 confirmed cases, 38 (35\%) were males and 72 (65\%)were females.Of the 72 female patients 42 were pregnant and majority, (83\%)were in the third trimester.Most of the patients were in the age group 20-30yrs (59\%). Total no. of deaths were 10 (9\%). Pregnancy was not associated with increased mortality (4.8\%and 11.8\%, P value.215). Initiation of Oseltamivir within 48 hours was associated with significant reduction in mortality (1.3\% and 29\%, P value\<.001).View this table:Table 1. Statistical analysisPresence of associated co morbidities were not associated with any increase in mortality rate (16.7\% and 6.3\%, P value.09)}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/38/Suppl_55/p4355}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }