RT Journal Article
SR Electronic
T1 Pleuro-pulmonary changes in patients suffering from end-stage renal disease receiving regular hemodialysis
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p3617
VO 38
IS Suppl 55
A1 Rabab El Wahsh
A1 Ali Zaki
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p3617.abstract
AB Introduction: End-stage renal disease (ESRD) was defined as a life-threatening reduction in glomerular filtration rate resulting in the requirement for hemodialysis, peritoneal dialysis or renal transplantation to maintain life. Pulmonary complications are an important cause of morbidity and mortality in patients with ESRD and infection is the second leading cause of death among them.Aim: To study pleuro-pulmonary changes and complications among patients with ESRD maintained on regular hemodialysis.Patients and methods: The current study included 20 patients with ESRD on regular hemodialysis for at least 6 months. For every patient, clinical, laboratory, arterial blood gases, radiological study of chest and heart and spirometric study were done.Results: Among the studied patients, 55% had pulmonary complications in the form of pulmonary infections, pleural effusion, pulmonary edema or hypoxemia during the course of hemodialysis. Spirometric measures, before and after hemodialysis, showed no significant improvement of VC, FVC, FEV1/FVC or MMV, whereas improvement in FEF25-75% and PEFR was significant. Significant hypoxemia occurred during hemodialysis. Significant improvement in pH, paCO2 and HCO3 occurred during and after hemodialysis.Conclusion: Patients with ESRD treated with hemodialysis must be considered at high risk for the development of lethal pulmonary complications. Regular hemodialysis improves arterial blood gases parameters and some pulmonary function measurements.