RT Journal Article SR Electronic T1 Effect of BMI on asthma control, asthma severity and quality of life in adult patients with asthma JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP p4928 VO 38 IS Suppl 55 A1 Aysegul Altintop A1 Haydar Karakus A1 Zeynep Aytemur A1 Suleyman Hacievliyagil A1 Hilal Ermis A1 Munevver Erdinc YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/p4928.abstract AB We examined effects of body mass index (BMI) on quality of life, asthma severity and treatment response of disease in patients with asthma.Demographic data, occupation and education status, symptoms, smoking, allergy, atopy, additional diseases, age started asthma, age diagnosed asthma, and drugs of subjects were recorded, and body mass index was (BMI) calculated. Hospital-Anxiety Depression Scale (HADS), Asthma Quality of Life Questionnaires (AQLQ) in the subjects were evaluated.The sample consisted of 414 subjects (73% female) with a mean age of 47,6±13,8 years. Regarding chronic severity, 9,8% were intermittent, 63,2% mild persistent, 24,4% moderate persistent, and 2,6% severe persistent. Furthermore, 44,1% of the subjects were controlled asthma, 47,9% partly controlled,%8 uncontrolled. Patients were considered to be obese if their BMI was ≥30 kg/m2. BMI was mean 26,62±5,37 kg/m2 in men and 28,88±6,21 kg/m2 in women (p<0.05). There was no correlation between BMI and severity of asthma, asthma control. There was a positive correlation between BMI and age started asthma (p<0.05). Regarding AQLQ results, there were negative correlations between scores of symptoms, activity limitations, emotional function, environmental stimuli and severity asthma (p<0.05). There were negative correlations between only environmental stimuli, activity limitations and BMI (p<0.05). There was no correlations between BMI and HADS depression-anxiety scores, physician-diagnosed depression-anxiety.Our findings suggest that obesity is associated with poor asthma-specific quality of life. BMI control was important as well as optimal asthma therapy in patients with asthma for optimal asthma control.