RT Journal Article
SR Electronic
T1 Second primary lung cancers developed following different system tumors
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p2814
VO 38
IS Suppl 55
A1 Cigdem Ozdilekcan
A1 Sevim Turanli
A1 Necla Songur
A1 Huseyin Cakmak
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p2814.abstract
AB Aims and background: This study aimed to investigate clinical characteristics and prognosis of secondarily developed lung tumors in the cases having different system malignancy and to evaluate the relationship with the primary tumor.Methods: Thirty patients diagnosed as second primary lung cancer those admitted to have been included in the study.Results: The patients were grouped; synchronous group (n:7, 16.7%) and metachronous group (n:2, 83.3%). The age of primary malignancy and second primary lung malignancy was median 59.5 (range, 38-82 years), and 63 years (range, 39-83 years) respectively. The rate of quitting smoking among all patients before the diagnosis of lung cancer was 50%, current smoker rate was 30%. Second cancer was detected in 50% of the patients within the first 2.5 years. The most frequent primary localization was larynx (40%). Majority of patients received surgical treatment for primary localized carcinoma, while for secondarily developed carcinoma, the most frequent treatment choice was chemotherapy and/or best supportive care. There was no statistical relationship between the response to treatment of first cancer and the duration of cancer developed secondarily (p=0.36). The overall survival of groups was found 24 months (95% confidence interval: 18.30 months) and 12 months (95% confidence interval: 10-14 months) respectively for synchronous and metachronous groups.Conclusions: Close follow-up on pulmonary system especially within the first 2.5 years after primary disease and encouragement on quitting smoking is important.