PT - JOURNAL ARTICLE AU - Izhaq Masih AU - Anne Breen AU - Shepherd Richard AU - Cecelia O'Kane TI - A 3 year (2007-2010) tuberculosis treatment analysis in Belfast City Hospital, Northern Ireland DP - 2011 Sep 01 TA - European Respiratory Journal PG - p2632 VI - 38 IP - Suppl 55 4099 - http://erj.ersjournals.com/content/38/Suppl_55/p2632.short 4100 - http://erj.ersjournals.com/content/38/Suppl_55/p2632.full SO - Eur Respir J2011 Sep 01; 38 AB - Introduction: Tuberculosis is on the rise globally. Northern Ireland is facing the enormous task to identify, diagnose and treat tuberculosis. Anti-tuberculosis treatment can be tedious and the side effects can hamper management and outcome.Objectives: To note the prevalence among local and immigrant patients, ascertain the HIV status and concordance and tolerance of ant-tuberculosis drugs.Methods: A retrospective clinical notes review, microbiology and biochemistry laboratory record analysis.Results: In total 92 patients, half were originally from Northern Ireland [Table]; 61% male and 39% female. The mean age was 50 (± 21) years with a bimodal age distribution between immigrants (36±11 years) and local patients (66.5±15.5 years).View this table:Table 1The majority (67%) had pulmonary and 20.5% had lymph node involvement. Rest had skin, bone, peritoneum, and psoas abscess disease. Culture positive were 76% and smear positive 45%. The majority (79%) were fully and 4% were partially sensitive to the treatment. One patient was multi-drug resistant. Four percent had HIV. The commonest side effect was minor GI upset (7%). Hepatitis and arthralgia occurred in 5.5%, minor skin reactions in 3%, and renal impairment, peripheral neuropathy, febrile reaction and retrobulbar neuritis in 2% each. Seven percent of patients received directly observed therapy.Conclusion: Tuberculosis is increasingly prevalent among the local population. Only 4% were HIV positive. Good drug compliance was observed in two third of patients. Treatment was modified in 24%, no treatment was stopped.