TY - JOUR T1 - Importance of controlled blood pressure values in a population with obstructive sleep apnea syndrome (OSA) and arterial hypertension (HT) JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p2225 AU - Oana Claudia Deleanu AU - Andra Elena Malaut AU - Ramona Elena Nedelcu AU - Ruxandra Ulmeanu AU - Ion Mierlus-Mazilu AU - Florin Dumitru Mihaltan Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p2225.abstract N2 - Rationale: OSA and HT are associated through cause-effect relationship, but few data in literature studies the effect of blood pressure (BP) control medication on OSA.Methods: We analised 162 OSA patients with treated HT, 46.9% with controlled BP (cBP), 53.1% with uncontrolled BP (uBP), and studied differences between groups regarding demographics, anthropometric data, symptoms, comorbidities, sleep study's reports, therapy. We use SPSS (T, chi tests)ListenRead phonetically.Results: 76 cBP patients: 22 (28.9%) women, 54 (71.1%) men, mean age 55.7±10.8 years, average apnea-hipopnea index (AHI) 49.5±36.5/h; 86 uBP patients: 20 (%) women, 66 (%) men, mean age 55.3±8.9 years, average AHI 58.1±38.7/h. Statistically significant differences (p <0.05): Epworth sleepiness score (9.70±5.61 in cBP group vs 11.65±5.61), snoring, morning headache, nocturnal dyspnea - more common in uBP group, nicturia - more common in cBP group, period elapsed since diagnosis (higher for uBP), AHI postCPAP (13.5±13.3 vs 21.5±19.9 cm H2O for uBP), explained by the higher proportion of CPAP failure among uBP (12.8% vs 5.2%). The hypothesis regarding existing differences related to the cardiovascular comorbidities is not supported.Conclusions: Controled blood pressure deletes sleepiness and reduces some other symptoms. The results is that OSA is more difficult to suspect in these patients, who, according to the results of this study, would benefit more from CPAP therapy. OSA may coexist in patients with HT controlled by medication in the absence of symptoms or signs and the patient, mostly young or middle-aged adult, cannot receive adequate treatment. ER -