%0 Journal Article %A Nina Karoli %A Andrey Rebrov %T Pulmonary hypertension and right ventricular impairment in patients with interstitial pneumonia %D 2011 %J European Respiratory Journal %P p3751 %V 38 %N Suppl 55 %X There is little date about frequency of pulmonary hypertension (PH) and right ventricular (RV) impairment in patients with idiopathic interstitial pneumonia (IIP). In this work we examined the prevalence PH in these disorders using noninvasive cardiopulmonary evaluation.40 patients (aged 50,33±2,55) with IIP have been studied in early period after IIP diagnosed. Criteria of exception were the clinical displays heart disease, arterial hypertension. Control group have made 14 normotensive volunteers (aged 47,57±1,86). All patients were studied using realtime, phased array, two-dimensional Doppler echocardiography. The pulmonary artery systolic pressure (SP) was calculated as the sum of the transtricuspid pressure gradient and the right atrial pressure.Results: Pulmonary hypertension (SP>35 mm Hg) is revealed at 15 patients with IIP and SP>40 mm Hg – at 7 (17.5%). Doppler-estimated SP at the patients with IIP exceeded SP at the healthy persons (33,24±1,97 mm Hg and 25,61±1,18 mm Hg, p<0.001). RV hypertrophy was present in 23 (57.5% patients (p<0.001), RV dilation was present in 76,5% patients with IIP (p<0.001). RV diastolic dysfunction was revealed in 65% patients. Right atrial diameter in patients with IIP was significantly higher than at the healthy persons (p<0.001). RV wall in patients with IIP was significantly higher than at the healthy persons (p<0.001). RV diastolic dysfunction we revealed in 56% pts.We noted correlations between SP and dyspnoe intensity (scale MRS) (r=0,63, p<0,01), VC (r=-0,61, p<0,01), FVC (r=-0,39, p<0,01), FEV1 (-0.38, p<0.01), SaO2 (r=-0,58, p<0,01).Conclusion: Pulmonary hypertension and right ventricular abnormalities is common in patients with IIP. %U