RT Journal Article SR Electronic T1 Factors affecting mortality in a respiratory intensive care unit JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP p2058 VO 38 IS Suppl 55 A1 Pelin Ozdemir A1 Burcu Basarik A1 Mehmet Sezai Tasbakan A1 Alev Gurgun A1 Ozen Kacmaz Basoglu A1 Feza Bacakoglu YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/p2058.abstract AB Introduction and aim: Underlying diseases, comorbidities and hospital acquired infections are the main factors that affect mortality in intensive care unit (ICU) patients. In this study, the factors affecting mortality in respiratory ICU were evaluated.Methods: The ICU patients followed-up between February 2008 and September 2010 were assessed retrospectively. The relationship between mortality and demographic features, underlying diseases, comorbidities, APACHE II and SAPS II scores on admission, invasive diagnostic and therapeutic procedures and, hospital acquired infections were investigated.Results: Out of 240 patients (165 men, mean age 58.2±16.6 yrs) included in the study, 118 patients (49.2%) died. The mortality rate was higher in immunosuppressive patients than immunocompetent ones (71.4% vs. 41.2%, p<0.0001). The age, APACHE II and SAPS II scores were higher in patients who died (p=0.007, p<0.0001, p<0.0001, respectively). The mortality rate was 66.2% in patients treated with invasive mechanical ventilation (IMV), whereas it was 38.6% in patients using noninvasive mechanical ventilation (p=0.0001). The mortality rate was higher in patients with positive culture of respiratory samples on admission, 3rd and 7th days (p<0.05). Besides, the durations of intubation (p<0.0001) and ICU stay (p=0.020) were longer in patients who died.Conclusion: Immunosupression, severity of illness, IMV requirement and development of lower respiratory infections were the most important factors affecting ICU mortality.