PT  - JOURNAL ARTICLE
AU  - Pelin Ozdemir
AU  - Burcu Basarik
AU  - Mehmet Sezai Tasbakan
AU  - Alev Gurgun
AU  - Ozen Kacmaz Basoglu
AU  - Feza Bacakoglu
TI  - Factors affecting mortality in a respiratory intensive care unit
DP  - 2011 Sep 01
TA  - European Respiratory Journal
PG  - p2058
VI  - 38
IP  - Suppl 55
4099  - http://erj.ersjournals.com/content/38/Suppl_55/p2058.short
4100  - http://erj.ersjournals.com/content/38/Suppl_55/p2058.full
SO  - Eur Respir J2011 Sep 01; 38
AB  - Introduction and aim: Underlying diseases, comorbidities and hospital acquired infections are the main factors that affect mortality in intensive care unit (ICU) patients. In this study, the factors affecting mortality in respiratory ICU were evaluated.Methods: The ICU patients followed-up between February 2008 and September 2010 were assessed retrospectively. The relationship between mortality and demographic features, underlying diseases, comorbidities, APACHE II and SAPS II scores on admission, invasive diagnostic and therapeutic procedures and, hospital acquired infections were investigated.Results: Out of 240 patients (165 men, mean age 58.2±16.6 yrs) included in the study, 118 patients (49.2%) died. The mortality rate was higher in immunosuppressive patients than immunocompetent ones (71.4% vs. 41.2%, p<0.0001). The age, APACHE II and SAPS II scores were higher in patients who died (p=0.007, p<0.0001, p<0.0001, respectively). The mortality rate was 66.2% in patients treated with invasive mechanical ventilation (IMV), whereas it was 38.6% in patients using noninvasive mechanical ventilation (p=0.0001). The mortality rate was higher in patients with positive culture of respiratory samples on admission, 3rd and 7th days (p<0.05). Besides, the durations of intubation (p<0.0001) and ICU stay (p=0.020) were longer in patients who died.Conclusion: Immunosupression, severity of illness, IMV requirement and development of lower respiratory infections were the most important factors affecting ICU mortality.