PT  - JOURNAL ARTICLE
AU  - Parvaneh Baghaei Shiva
AU  - Payam Tabarsi
AU  - Majid Marjani
AU  - Mohammad Reza Masjedi
TI  - Adverse effects of treatment in HIV-associated tuberculosis patients in Iran
DP  - 2011 Sep 01
TA  - European Respiratory Journal
PG  - p1940
VI  - 38
IP  - Suppl 55
4099  - http://erj.ersjournals.com/content/38/Suppl_55/p1940.short
4100  - http://erj.ersjournals.com/content/38/Suppl_55/p1940.full
SO  - Eur Respir J2011 Sep 01; 38
AB  - Background: We intend to assess the frequency of adverse effects of tuberculosis treatment in HIV patients.Methods: The study was conducted at National Tuberculosis referral center in Iran, 2005-2010 including all documented TB patients with HIV co-infected. All patients received anti-TB treatment based on National TB Program. All adverse effects (AE) observed in patients were recorded in our registry.Results: Of the total 151 TB/HIV patients, 81 (53.6%) developed adverse effects (AE) whether major or minor. Major AE (65) included hepatitis (46), convulsion (4), thrombocytopenia (17), rash (5) that 86.2% of them had CD4<100 (p<0.001). There were no differences between uses of HAART, outcome of treatment and major AE. Other AE did not show statistical significant in our study.Conclusion: This study showed that major adverse effects do not affect to outcome of TB treatment.