RT Journal Article
SR Electronic
T1 Efficiency of nebulised therapy in preventive maintenance of bronchial stump insufficiency after pneumonectomy
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p2416
VO 38
IS Suppl 55
A1 Shuhrat Hudaybergenov
A1 Georgy Pahomov
A1 Rustem Hayaliev
A1 Ortikali Irisov
A1 Otabek Eshonhodzhaev
A1 Ezoz Rizaev
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p2416.abstract
AB Introduction: Introduction for preventive maintenance COPD nebulised therapy (NT) promotes the high local activity of inhalated remedies.Purpose: To value efficiency of NT in preventive maintenance of bronchial stump insufficiency (BSI) after pneumonectomy (PE).Material and methods: The interesting results were received at study of the influence accompanying pathology on frequency of development BSI after PE. The frequent diseases were COPD and heart-vascular pathology. So from 390 patients in 207 (53,1%) accompanying COPD was revealled, on background which after PE in 36 (17,4%) patients was noted development of BSI. In turn, amongst 183 (46,9%) patients without accompanying COPD this complication was noted only in 2,7% of the cases. That is to say, presence of COPD raised the risk of the development BSI more then in 6 once.Results: Introduction NT has allowed in the main group to reduce the risk of the intensification COPD to 16,1% after PE on the left and 17,2% after PE on the right, and frequency of the development of BSI on background accompanying COPD decreased to 3,2% and 6,9% accordingly. In the main group accompanying COPD was revealled in 60 patients (61,2%), activation after operation was noted in 10 (16,7%) patients, but development of BSI only in 3 patients, that has formed 5,0%.Findings: Introduction of NT for preventive maintenance COPD promotes not only reliable improvement of the factors of breathing frequency (P<0,002) and functional respiratory tests (P<0,001), but also reduction of the frequency of the intensification of obstructive syndrome from 52,4% to 16,7% that led to reduction of the risk of development BSI from 16,5% to 5,0%.