TY - JOUR T1 - HRCT score to control and evaluate the prognosis in idiopathic pulmonary fibrosis JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p654 AU - Ricardo Peris AU - Estrella Fernandez-Fabrellas AU - Ignacio Inchaurraga AU - M. Luisa Domingo AU - Julio Palop AU - Rafael Blanquer Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p654.abstract N2 - Introduction: HRCT is not commonly used to assess the severity of idiopathic pulmonary fibrosis (IPF).To assess: We sought to evaluate the usefulness of a semiquantitative HRCT score and its relation with respiratory function tests normally used to ascertain IPF severity and to monitor the evolution and progression of the fibrotic process.Patients and methods: A prospective 4 years study including 36 consecutive IPF patients. A semiquantitative score was used to score every predefined IPF 4 patterns on HRCT. As a result of summing up all of them we had the Total Score of Fibrosis for each patient.We studied its relation with functional respiratory tests, bronchoalveolar lavage (BAL) cellularity and analyzed the differences found among the death patients.Results: We found a significant correlation between the honeycomb score and% DLCO (r= -0.48, p=0.004), total score of fibrosis with% FEV1 (r= -0.41, p=0.01),% DLCO (r= -0.41, p=0.01) and% TLC (r= -0.36, p=0.03). The 6-minutes walking test (6MWT): the final SaO2 correlated with the total score (r= -0.48, p=0.04). A-aO2grad also correlated with the honeycomb score (r=0.43, p= 0.01) and the total score (r=0.48, p=0,005). Dead patients had a higher total score and a tendency of higher neutrophilia in BAL (p=0.059).Conclusions: A semiquantitative score of HRCT is useful in assessing the initial severity of IPF and should be able to predict its development. ER -