PT - JOURNAL ARTICLE AU - Eleni Kortianou AU - Ioannis Vogiatzis AU - Zafeiris Louvaris AU - Maroula Vasilopoulou AU - Ioannis Nasis AU - Vasilis Andrianopoulos AU - Theodora Vasilogiannakopoulou AU - Giorgos Kaltsakas AU - Manos Alchanatis AU - Nikolaos G. Koulouris TI - Combining physical activity monitoring and cardiac output during exercise in COPD patients with GOLD stages II-IV DP - 2011 Sep 01 TA - European Respiratory Journal PG - 210 VI - 38 IP - Suppl 55 4099 - http://erj.ersjournals.com/content/38/Suppl_55/210.short 4100 - http://erj.ersjournals.com/content/38/Suppl_55/210.full SO - Eur Respir J2011 Sep 01; 38 AB - Background: Daily physical activity recorded by activity monitors, is an important clinical outcome in COPD patients. However, it is unknown whether changes in physical activity data are related to changes in hemodynamic responses during exercise.Aim: To investigate whether changes in estimated energy expenditure (EE) by activity monitoring are associated with changes in cardiac output (CO) during exercise.Methods: 30 COPD patients (10 for each GOLD stage:II,III,IV) undertook a standardized treadmill test including breath-by-breath gas exchange measurements. Cardiac haemodynamics was assessed by impedance cardiography. The SenseWear armband (SW) and the DynaPort Minimod (MM) were used to estimate EE. All patients exercised at 4 different velocities increasing by 0.7-0.8 km/h every 3 min. Minimum and maximum speeds were 1.4±0.3 km/h and 3.7±0.4 km/h, respectively. Minute-by-minute data were acquired and aligned for each patient.Results: CO was linearly increased with increasing speeds (r=0.97). Median and interquartile range of the correlation between CO and EE by SW and MM are shown below. The level of correlation between CO and EE was not different across GOLD stages and between the two activity monitors.View this table:Median and interquartile range of the correlation between CO & EEConclusion: Hemodynamic variations during incremental treadmill exercise in COPD were reliably reflected by changes in EE as those were recorded by the SenseWear armband and the Dynaport Minimod. Supported by IMI-JU Proactive#115011.