@article {Alpaydinp532, author = {Aylin Ozgen Alpaydin and Mine Bora and Arzu Yorgancioglu and Aysin Sakar Coskun and Pinar Celik}, title = {The association between the asthma control test and the asthma quality of life questionnaire in adult asthmatics}, volume = {38}, number = {Suppl 55}, elocation-id = {p532}, year = {2011}, publisher = {European Respiratory Society}, abstract = {Aim: Asthma control and quality of life are expected to be correlated. We aimed to evaluate the association of asthma control test (ACT) with asthma quality of life questionnaire (AQLQ) and guideline based control assessment. We also aimed to investigate the impact of therapy adjustment according to ACT score on AQLQ levels.Methods: A total of 101 consecutive, stable asthmatic patients between 18 and 55 years were included in the study. ACT and AQLQ were administered, GINA based control assessment was performed. Based on ACT control status, treatment was adjusted by stepping down in controlled, stepping up in uncontrolled and some well controlled patients. In some controlled and well controlled patients no therapy adjustment was done. After 3-months ACT and AQLQ were repeated.Results: Mean age of the patients (82 female) was 42{\textpm}11. According to GINA 22\% were controlled, 20\% were partly controlled and 59\% were uncontrolled. Median and range for ACT score was 20 (16-23), while mean AQLQ total score was 4.59{\textpm}0.94. We determined a significant association between ACT and AQLQ activity, symptom and environmental stimuli domain scores and total score (r=0.651, 0.697, 0.348, respectively, p\<0.001). ACT scores increased in the step-up group (p\<0.001), however AQLQ total scores were not affected. We found ACT concordant with GINA recommended control classification in the first (kappa=0.511, 7.718) and third months (kappa=0.599, 7.912) (p\<0.001 for both).Conclusion: We determined an association between ACT and AQLQ. ACT was also found fairly concordant with GINA. However, treatment adjustment according to ACT was not found satisfactory in terms of quality of life.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/38/Suppl_55/p532}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }