RT Journal Article SR Electronic T1 Clinical and economical impact of exacerbations of chronic obstructive pulmonary disease (COPD): A two-year study JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP p3010 VO 38 IS Suppl 55 A1 Francesco Blasi A1 Carla Fornari A1 Francesca Di Stasi A1 Sara Conti A1 Lorenzo Giovanni Mantovani A1 Luca Merlino A1 Stefano Aliberti A1 Giancarlo Cesana YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/p3010.abstract AB COPD is a common disease with considerable health and economic consequences. The aim of our study was to analyze clinical and economical impact of COPD exacerbations (E-COPD). A secondary data analysis of healthcare administrative databases of Lombardy, Italy was performed, including patients hospitalized for a severe E-COPD (index event) from Jan to Dec 2003. Two study groups were identified based on the number and type of E-COPD experienced after the index event during a two-year follow-up: those who had at least one severe E-COPD (Group A) and those who had only moderate E-COPD (Group B). A total of 12,436 patients (7,933 males; mean±SD age: 74±10 yrs) were enrolled. Among those, 45% belonged to Group A and 55% to Group B. Clinical outcomes, costs and consumptions of pulmonary function test (PFT) per person during the follow-up are given in Table.View this table:Mortality risk increased in the study population in relation to the number and type of E-COPD experienced during the follow-up. The number and type of E-COPD significantly impact outcomes and costs. Less than one fourth of patients discharged after an E-COPD will undergo a PFT during two years, although its cost is extremely lower than the hospital stay.