TY - JOUR T1 - The association between residential radon concentration and lung cancer JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p2733 AU - Doina Adina Todea AU - Loredana Elena Rosca AU - Constantin Cosma AU - Tiberius Dicu Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p2733.abstract N2 - Lung cancer represents the most frequent cause of mortality caused by malignancies in the world. Radon (Rn), the second recognized carcinogenic agent involved in the development of lung cancer, after smoking, is a noble gas with a high mobility. The aim of this study was to investigate the correlation between the exposure to radon and lung cancer in patients from the centre counties of Transilvania, Romania.Material and method: We conducted a case-control study, by location of 204 Rn detectors in 78 patients with lung cancer and 126 controls from the centre counties of Transilvania.Results: From 78 cases 87% were men, 13% were women, from 126 controls 57% were men, 43% women, 38% of cases were from urban area and 62% from rural area, 39% from controls were from urban area and 61% from rural area, the age average in cases was 65±11 and in controls 57±15, in cases 33% were with a family history of cancer and 13% were in controls. We observed that the magnitude of Rn exposure for cases was 139 Bq/m3 (average) minimum 9 Bq/m3, maximum 750 Bq/m3, geometric mean was 102 Bq/m3. The average for controls was 125 Bq/m3, minimum 9 Bq/m3, maximum 740 Bq/m3, geometric mean was 80 Bq/m3.Conclusions: The Rn concentrations are higher in patients with lung cancer compared with controls. This findings support the implication of Rn in developing lung cancer and the high level of Rn in studied area. ER -