TY - JOUR T1 - Sublinguial allergen extract immunotherapy in a rush pattern to reach the maintainance faster JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p262 AU - Naren Pandey AU - Saurabh Kole AU - Surendra Prasad Singh AU - Swati Gupta Bhattacharya AU - Suman Kumar AU - S. Bibhore Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p262.abstract N2 - Introduction: Slit (sub lingual immunotherapy Rush immunotherapy was tried on some patients to evolve some faster and affordable immunotherapy modality to make the patient achieve the maintenance pleatu within a very short time. Conventional method of immunotherapy is administered with long durations; rush immunotherapy is super fast methodology in attaining the maintenance/boosting module, which requires hospitalization and other precautionary methods, and multiple allergen vaccines to be administered within short span of time. But in this method, it was found that within 15-20 days the relief of the immunotherapy was reached.Material & method: 186 patients out of which 48 with urticaria allergy and 138 with allergic Rhinitis & Bronchial Asthma were selected. The therapy consists of administration of four vials of allergen extracts, 1st vial: 1:25,00, 2nd vial 1:2,50, 3rd vial 1:25, and 4th vial 1:10 dil. The 1st & the 2nd concs were administered in daily 6 hourly schedules in a graphically rising manner. The patients had been given pre-medication. Blood examination and IgG & IgE level estimation were done before & after 8 weeks.Results: Some of the patients showed local skin reactions which subsided without drugs and no systemic reaction was noted. There was substantial decrease in IgE & increased IgG level, significant & marked satisfactory relief was observed in the patients symptomatology, thus the procedure was graded as a very fast & affordable & SAFE immunotherapy. ER -