TY - JOUR T1 - Clinical features and outcomes of patients hospitalized with influenza A virus (H1N1) infection in a hospital of the south of Spain JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p4346 AU - Victoria Nuñez-Rodriguez AU - Mª Angeles Villena-Ruiz AU - Alicia Padilla-Galo AU - Silvia Soler-Mendez AU - Luis Fernandez de Rota-Garcia AU - Teresa Perez-Romero AU - Julian Olalla-Sierra AU - Jose Joaquin Cebrian-Gallardo AU - Jose Javier Garcia-Alegria Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p4346.abstract N2 - Aim: To describe the characteristics and outcomes of patients hospitalized H1N1 influenza infection.Methods: Retrospective analysis of the medical records of patients hospitalized with H1N1 infection in our hospital (August09/April10). All patients underwent nasopharyngeal PCR swab for H1N1. Results are expressed as mean ± standard deviation for quantitative variables.Results: 93 patients (18.34%) were positive for influenza A virus. The clinical features, risk factors and outcomes are available in the tables.View this table:Table 1. Risk FactorsView this table:Table 2. Clinical features and outcomesThe presenting symptoms were fever (89.2%), cough (92%), dyspnea (65.5%), digestive problems (26.9%), myalgia and headache (53%). 52.2% had community acquired pneumonia on admission. Major complications during hospitalization were (15.6%): respiratory insufficiency (50%), Acute Respiratory Distress Syndrome (8.9%), pneumothorax (3.3%), pleural effusion (1.1%) and multisystem organ failure (3.4%).Conclusions: Patients hospitalized for H1N1 infection are mainly middle-aged. Pneumonia and/or decompensate co-morbidities were the main causes of hospitalization. The most common risk factor was the chronic lung disease. ER -