RT Journal Article SR Electronic T1 Salvage lung resection for local recurrence after stereotactic body radiotherapy for primary and metastatic lung cancers JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP p2427 VO 38 IS Suppl 55 A1 Takuya Terashi A1 Hiroshi Hamakawa A1 Shinya Neri A1 Ei Miyamoto A1 Keisuke Tomii A1 Nobuyuki Katakami A1 Masaki Kokubo A1 Yutaka Takahashi YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/p2427.abstract AB Introduction: Stereotactic body radiotherapy (SBRT) has been proposed as an alternative to surgical resection for primary and metastatic lung cancers, for patients under inoperable condition based on poor lung function and/or senility. Sometimes, such patients refuse surgery and chose SBRT for the first treatment as a less invasive therapeutic option. However, surgical outcomes for local recurrence after SBRT were still unclear.Methods: To further understand the indication for salvage lung resection, we retrospectively reviewed 9 patients (3 with stageInon-small cell lung cancer and 6 with metastatic lung tumors) who underwent salvage surgical resection for local recurrence after SBRT.Results: Of the 9 patients, 7 underwent lobectomy, and the remaining 2 did bilobectomy and segmentectomy, respectively. 2 with metastatic lung tumors had pleural adhesion resulted from SBRT-related fibrosis. However, there was no case in which SBRT made surgical procedure impossible. Retrospectively considering the course after SBRT, once all 9 irradiated tumors resulted in disease progression, they grew in size rapidly.Conclusions: We have treated all patients without major technical difficulties by SBRT-related change. SBRT did not close the door to perform salvage surgical resection, and surgical resection might be feasible for local recurrence after SBRT. However, close follow-ups are mandatory for patients treated with SBRT because tumor regrowth after SBRT is thought to occur at a rapid rate. And if patients are medically fit for surgery as the first line treatment, the use of SBRT should not be decided by only reason of its less invasiveness.