@article {Irelandp4167, author = {Andrea Ireland and Ingela Wiklund and Peter Dale and Ray Hsieh and Erin O{\textquoteright}Rourke}, title = {Reproducibility of an asthma symptoms and rescue medication diary: Paper and AM3{\texttrademark} modes}, volume = {38}, number = {Suppl 55}, elocation-id = {p4167}, year = {2011}, publisher = {European Respiratory Society}, abstract = {Objective: This study investigated the test-retest reliability of a twice-daily (morning and evening) asthma symptoms and rescue medication diary within two modes of administration: 1) paper-and-pencil; and 2) AM3{\texttrademark} electronic device in patients with persistent asthma.Methods: Prospective cross-over study where key inclusion criteria were Asthma Control Test (ACT) scores >=16, ICS with or without LABA use, \<2 nocturnal awakenings due to asthma (past week), and activity limitations <=1 per week. Participants were randomly allocated to complete the diary in each mode for 15 days. Spirometry was performed at randomisation, cross over, and end of study and changes in asthma resource use were captured. Weekly percentage of symptom-free days (SFD) and rescue-free days (RFD) were calculated using diary data. Intraclass correlation coefficients (ICC) of mean Week 1 SFD and RFD (test) and Week 2 mean SFD and RFD (retest) were estimated for three groups of stable participants: 1) patient who reported little or no change in asthma symptoms and rescue use at Day 15; 2) \<{\textpm}15\% change in FEV1 (L); and 3) ACT change scores \<|3| (final visit versus baseline).Results: The mean age of the participants (n=50) was 36.5{\textpm}17.5 years. Independent of mode of administration, SFD demonstrated acceptable test-retest reliability (ICC>=0.70) based upon all three definitions of asthma stability. By comparison, acceptable reproducibility of the percentage of RFD (ICC 0.78) was only observed for the electronic diary using the FEV1 stability criterion.Conclusion: This study provides evidence of the test-retest reliability of SFD and RFD diary as well as concordance between the two modes of administration.Funded by GSK}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/38/Suppl_55/p4167}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }