@article {Smallp1203, author = {Therese Small and Christopher Ward and James Lordan and Andrew Fisher and Paul Corris and John Gibson}, title = {Static lung volumes in lung transplant recipients with bronchiolitis obliterans syndrome}, volume = {38}, number = {Suppl 55}, elocation-id = {p1203}, year = {2011}, publisher = {European Respiratory Society}, abstract = {The bronchiolitis obliterans syndrome (BOS), post lung transplantation, is defined and monitored by FEV1. Progressive pulmonary hyperinflation may accompany airway obstruction in BOS and assessing hyperinflation might give a more sensitive signal. However, after single lung transplantation (SLT), for chronic airway disease, the native hyperinflated native lung might compromise interpretation of lung volume measurements. We therefore compared plethysmographic lung volumes, including inspiratory capacity (IC), at the time of diagnosis of BOS in 2 groups of patients: post SLT and post sequential single lung transplantation (SSLT).We studied 32 patients: 11 SLT (9 COPD; 2 OB) and 21 SSLT (6 COPD; 1 OB; 14 cystic fibrosis). The SSLT group were significantly younger (median 38 v. 54 years).View this table:The SLT group had larger TLC and FRC, while IC was similar in the two groups and, as a proportion of VC, was actually greater in the SLT group.IC was relatively well preserved in the SLT patients with early BOS, despite the presence of a hyperinflated native lung. Longitudinal lung volume measurements might usefully evaluate the progress of BOS in both SLT and SSLT recipients.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/38/Suppl_55/p1203}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }