%0 Journal Article %A Mehrdad Bakhshayeshkaram %A Pooyeh Graili %A Soheyla Zahirifard %T Lymphoma diagnosis on computed tomography guided needle aspiration and biopsy %D 2011 %J European Respiratory Journal %P p3666 %V 38 %N Suppl 55 %X Background: In recent years, CT-guided biopsy is going to be replaced with open biopsy for Lymphoma diagnosis.Objectives: This study was designed to assess Lymphoma diagnosis on CT-guided biopsy and to identify the complication rate of procedure.Methods: We evaluated 78 CT-guided biopsies of mediastinal lesions performed from March 2004 to December 2008, retrospectively. All biopsies were performed by one radiologist. The CTs were assessed by a trained general practitioner for the size and location of lesions and pneumothorax or pneumomediastinum diagnosis and then all CTs were double checked by the same radiologist. Lesions considered benign or malignant and lymphoma based on pathology reports.Results: Biopsy yielded sufficient tissue for pathologic examination in 63 cases (80.77%); 14 lesions (17.9%) were benign and 49 lesions (62.8%) were malignant. In malignant masses 15 Lymphoma (30.6%) and 20 other kinds of tumors (46.8%) were found. Moreover, 1 1malignant lesions had no differentiation. Among Lymphoma lesions, there were 7 (46.7%) Hodgkin, 5 (33.33%) Non-Hodgkin Lymphoma and 3 (20%) Lymphoma without differentiation. Pneumothorax or pneumomediastinum as complications did not present in any case.Conclusion: CT-guided needle biopsy seems to be reliable as a less invasive diagnostic modality with low risk probability of complications for Lymphoma. %U