PT - JOURNAL ARTICLE AU - Valentina Rosti AU - Chiara Travierso AU - Federico Piffer AU - Stefano Aliberti AU - Caterina Bonino AU - Valter Monzani AU - Antonio Voza AU - Daniele Camisa AU - Simona Fusco AU - Marco Barchetti AU - Federica Molinaro AU - Giuseppina Petrelli AU - Roberto Cosentini AU - Anna Maria Brambilla TI - “Normotension” on admission to the emergency department affects outcome of patients with acute cardiogenic pulmonary edema (ACPE) DP - 2011 Sep 01 TA - European Respiratory Journal PG - p2046 VI - 38 IP - Suppl 55 4099 - http://erj.ersjournals.com/content/38/Suppl_55/p2046.short 4100 - http://erj.ersjournals.com/content/38/Suppl_55/p2046.full SO - Eur Respir J2011 Sep 01; 38 AB - Introduction: ACPE is a common cause of admission to the Emergency Department (ED). We previously retrospectively studied the effect on the outcome of blood pressure (BP) on admission.Aim: To prospectively confirm the relationship between “normotension” on admission and worse outcome in ACPE patients.Methods: Prospective, observational, multicentric, web-based study on patients admitted to the ED with ACPE. Data were collected from 13 italian EDs. Normotension was defined as Mean Arterial BP (MAP)≤107 mmHg. Patients with MAP≤65 mmHg on admission were excluded.Results: From May 2009 to October 2010,460 patients were enrolled. Nine hypotensive patients were excluded. Mean age was 80 years (SD±10 years), 245 males (54%). “Normotensive” patients were 41% (185/451). Clinical and laboratory data are showed in table 1. Overall, in-hospital mortality was 8% (34/451). In-hospital mortality in normotensive patients was significantly higher than in hypertensive patients, 12% (22/185) vs 4% (12/266) (p<0.01). We also found that the risk factor “normotension” maintained its statistical significance in a multivariable analysis when compared with the other significant risk factors (Age, PaCO2 and Hemoglobin) detected in our population in the univariate analysis.View this table:Table 1. Baseline characteristic of the two populationsConclusion: We prospectively confirmed that “normotension” on presentation is a significant and indipendent risk factor for mortality in patients with ACPE.