TY - JOUR T1 - Effects and feasibility of different types of endurance training in patients with end stage lung disease before lung transplantation JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - 1891 AU - Rainer Gloeckl AU - Bianca Weber-Lange AU - Martin Halle AU - Klaus Kenn Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/1891.abstract N2 - Objective: Aim of this study was to compare the effects and the feasibility of continuous moderate endurance training (CT) versus high-intensity interval training (IT) in patients with end-stage COPD before lung transplantation (pre-LTx) during a specialized 3-week in-patient pulmonary rehabilitation programme.Methods: 60 lung transplant candidates (age: 53.5±56.3 yrs; FEV1 pred. 24.9±7.9%) performed up to 15 training sessions within 3 weeks randomised either to CT (n=30) or IT (n=30). CT was characterised by cycling at 60% Wmax whereas IT consisted of 30 sec exercise (100% Wmax) and 30 sec rest. Total amount of exercise time per session in CT increased from 10 to 30 min respectively from 12 to 36 min in IT yielding equivalent volume of exercise.Results: Both groups achieved similar improvements in 6MWD. The CT group increased by 35.7±42,21m from baseline 312.7±98.2m and the IT group by 35.4±27,89m from 289.5±108.7m. Despite an increase in cycling time, patients in both groups showed decreased symptoms of dyspnoea during exercise. The overall dyspnoea over the whole training period was significantly (p=0.018) higher in CT (BORG 7.1) than in IT (BORG 6.2). Furthermore, significantly (p<0.001) more unintended interruptions during exercise were observed in CT (28.3) than in IT (7.2).Conclusion: Our study shows, that CT as well as IT can significantly improve exercise capacity in pre-LTx patients. IT seems to be better tolerated, expressed by a lower grade of dyspnoea and significantly better feasibility of the exercise protocol. ER -