RT Journal Article
SR Electronic
T1 Development and clinical testing of a device for functional bronchoscopy
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p3697
VO 38
IS Suppl 55
A1 Lutz Freitag
A1 Kaid Darwiche
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p3697.abstract
AB We have developed a universal interface that enables to observe and process physiological data during flexible bronchoscopy. Various sensors for measuring flows, pressures, CO2 and other gas concentrations, pulse oximetry and optical spectra are built into a block that is placed next to the patient's head. It also contains an emphysema valve simulator. Sensing catheters are guided through the working channel of the bronchoscope. Curves and values are displayed on the video-screen, superimposed over the endo-image. All are stored and processed in real time. So far, the system has been used in more than 150 patients. Measuring mouth air-flow while observing the larynx enables to validate vocal chord dysfunction at rest and during exercise. Internal flow and pressure measurements combined with airway planimetry are useful to identify and quantify malacias. Examples are shown demonstrating bronchoscopy guided lobar lung function tests with measurement of collateral ventilation, lobar gas exchange and perfusion. Together with the built-in valve simulator it facilitates individually tailored endoscopic emphysema treatment. Using the optical catheter, auto-fluorescence and drug-induced fluorescence of the mucosa is measured for cancer detection and photodynamic therapy.The simultaneous measurement of physiological data and the bronchoscopic image broadens the application of bronchoscopy, helps to solve diagnostic puzzles and has proven to be extremely useful for endoscopic treatment planning.