RT Journal Article SR Electronic T1 Missed opportunities to diagnose COPD JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 182 VO 38 IS Suppl 55 A1 David Price A1 David Halpin A1 Robert Winter A1 Susan L. Hill A1 Eric Bateman A1 Daryl Freeman A1 Dermot Ryan A1 Matthew Kearney A1 Kevin Holton A1 Annie Burden A1 Julie von Ziegenweidt A1 Laurence Mascarenhas A1 Alison Chisholm A1 Rupert Jones YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/182.abstract AB Rationale: Early diagnosis and intervention in the management of symptomatic chronic obstructive pulmonary disease (COPD) may reduce the associated impact on patients and economic burden on health systems.Objective: Characterise healthcare utilisation in the yrs preceding a definitive COPD diagnosis to identify “red flags” that may aid in earlier diagnosis.Method: Retrospective observational study using pooled routine practice data from the General Practice and Optimum Patient Care Research Databases. Patients were: ≥40 years, received a COPD diagnosis between 1990–2009; were prescribed ≥2 COPD therapies in the yr following diagnosis, and had ≥2yrs of continuous practice data prior to their diagnosis. Non-routine healthcare resource utilisation was monitored in the yrs preceding COPD diagnosis.Results: 38,859 eligible patients: 52.6% male, diagnosis with COPD at median (IQR) age of 68 (60–75) years. In the 2yrs prior to diagnosis, 56.4% consulted on multiple (≥2) occasions for lower respiratory (LR) complaints, 26.5% for lower respiratory tract infections. Of these, 34.5% received multiple prescriptions for oral steroids (71.4%) and/or antibiotics (82.5%). These patients also recorded more respiratory outpatient visits over the 10yrs, and inpatient hospitalisations over the 4yrs, prior to diagnosis. Significantly more patients diagnosed in secondary care (or within 2-weeks of a hospital admission) had received multiple LR prescriptions in the prior 2yrs than patients diagnosed in primary care (40.7%vs34.5% p=0.007).Conclusion: The data suggest increased use of non-routine respiratory resource by patients in the 2- to 10-yrs prior to their COPD diagnosis suggesting opportunities for earlier COPD diagnosis and/or assessment may be missed in the UK.