TY - JOUR T1 - Late-breaking abstract: Evaluation of CRP, PCT, clinical pulmonary infection score and pneumonia severity scores for the diagnosis and prognosis of nursing home acquired pneumonia JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - 179 AU - Ilias Porfyridis AU - Georgios Georgiadis AU - Paris Vogiazianos AU - Andreas Georgiou Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/179.abstract N2 - Introduction: Nursing home acquired pneumonia (NHAP) represents a distinct group of respiratory infections with different risk factors, clinical presentation and higher mortality than CAP.Aim: To evaluate the diagnostic value of clinical pulmonary infection score (CPIS), CRP and PCT and compare the accuracy of CURB-65, pneumonia severity index (PSI), nursing home acquired pneumonia (NHAP) index, SMART-COP and SOAR in predicting in-hospital mortality of NHAP.Methods: 49 residents in nursing homes admitted to pulmonary department were enrolled in the study. Pneumonia severity scores were recorded. CRP and PCT were measured by immunonephelometry and immunochromatografy respectively.Results: 39 patients were diagnosed with NHAP (group A) and 10 with other pulmonary disorders (group B). Mean ± SE CRP was 16.53±1.65mg/dl in group A and 5.26±2.56mg/dl (p=0.002) in group B. Mean ± SE PCT was 1.78±0.39ng/ml in group A and 0.5±0.09ng/ml (p=0.001) in group B and mean± SE CPIC was 5.7±0.18 in group A and 2±0.53 (p<0.001) in group B. The in-hospital mortality was 17.9% in group A.PCT and CRP were accurate in predicting mortality with AUC of 0.8 (95%CI 0.61-0.98) and 0.67 (95%CI 0.41-0.92) respectively. SMART-COP, SOAR and PSI performed similarly with AUC 0.38 (95%CI 0.17-0.6), 0.52 (95%CI 0.3-0.75) and 0.57 (95%CI 0.36-0.77) respectively, whilst CURB65 [AUC 0.66 (95%CI 0.45-0.86)] and NHAP index [AUC 0.6 (95%CI 0.39-0.8)] showed superior accuracy in predicting mortality.Conclusion: The CPIS, PCT and CRP are reliable for the diagnosis of NHAP. PCT, CRP and CURB65 were accurate for predicting in-hospital mortality in patients with NHAP. ER -