RT Journal Article SR Electronic T1 Physical rehabilitation in asthma management JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP p4803 VO 38 IS Suppl 55 A1 Natalia Astafieva A1 Denis Kobzev A1 Inna Gamova A1 Irina Perfilova A1 Ekaterina Udovichenko YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/p4803.abstract AB Background: 50% of asthma patients experiences limitations in physical activity and usual lifestyle. Gymnastics can provide significant health benefits and improve quality of life.Objective: To investigate effects of gymnastics on asthma patients, specifically leading to ameliorated lung function.Methods: A prospective, randomized, controlled trial was performed to evaluate the effect of respiratory gymnastics (RG). 85 patients with moderate/severe asthma were randomly assigned to control (CG - 16 persons, standard therapy) or RG (RGTG - 69 persons, standard therapy & RG) group; with no significant difference in demographics. Patients were instructed how to practice exercises and examined in 3-6-9-12 months for pulmonary function, cardiopulmonary exercise and control of asthma.Results: 12 month physical rehabilitation (with pharmacotherapy) reduced: the frequency of complaints; clinical manifestations of asthma; symptoms: daytime (from 94.0% to 28.0%; p = 0.0001) and night (from 54,7% to 7,1%; p = 0,0001); the consumption of β2-agonists (from 3,2 to 2,1 puffs/week). RGTG group increased: FEV1 (from 1,3 to 1,7 L); PEF (from 338,6±19,5 to 403,5±15,8); exercise capacity (W/kg) from 0.85±0.1 to 1.4±0.1. The number of patients with limited physical activity decreased from 86.0±5.0 to 22.0±5.9%; p = 0,001. Heart rate and blood pressure recovery time after exercise decreased from 10,4±0,7 to 9,1±0,6 min (p <0,05). CG changes were much lower (difference between groups was significant, p < 0,001).Conclusions: Individual programs of RG reduced asthma symptoms and the use of bronchodilator medication in patients with asthma, and can be effective as an adjuvant therapy and optimize asthma patients medical treatment.