@article {Kholtobinp2695, author = {Denis Kholtobin and Ekaterina Kulchavenya}, title = {Kidney tuberculosis in last century and now {\textendash} Is it the same disease?}, volume = {38}, number = {Suppl 55}, elocation-id = {p2695}, year = {2011}, publisher = {European Respiratory Society}, abstract = {Kidney tuberculosis (KTB) has non-specific clinical features and mimics on different other urological diseases: urolithiasis, cancer, pyelonephritis, cystitis etc. Moreover clinical features are not stable for ages, they change rather quickly.The aim was to compare KTB in Siberia in 1980-1990 (1st group, 268 patients) and in 2000-2005 (2nd group, 227 patients), all were in-patients of Urogenital Department of Novosibirsk Research TB Institute.A flank pain in 1st group was rarer (58.9\% and 72.8\% accordingly), but frequency of dysuria was the same (57.1\% and 54.3\%). Frequency of renal colic decreased from 16.1\% up to 12.3\%; haematuria increased from 30.4\% up to 48.1\%. Pyuria left most common laboratory sign {\textendash} 91.7 {\textendash} 91.4\%. Significantly reduced a frequency of positive cultures {\textendash} mycobacteriuria was revealed in 84.5\% in first group and in 44.0\% only in novo days.Asymptomatic course was about equal {\textendash} 8.9\% and 6.2\%, but frequency of acute debut changed significantly. In 1st group 34.5\% patients got sick acutely, with manifesting clinical features, fever, pain etc. In second group the same patients there were 4.9\% only. On contrary, obscure, vogue symptoms were in 56.6\% in 1st group and in 88.9\% - in 2nd group.Mean age was stable: 40.5 in 1st group and 43.8 in 2nd group. A rate male: female was about 2:3 in both groups.Conclusion: We can speak about clinical pathomorphosis of KTB. Clinical features of KTB has changed in last years. In 7 times rarer became acute onset of KTB, significantly more often patients have flank pain and haematuria now. Asymptomatic course of KTB is possible too. All this may be a reason for late diagnosis.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/38/Suppl_55/p2695}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }