PT - JOURNAL ARTICLE AU - Raphael Heinzer AU - Daniela Andries AU - Francois Bastardot AU - Nadia Tobback AU - Peter Vollenweider AU - Mehdi Tafti AU - José Haba-Rubio TI - Prevalence of sleep disordered breathing in middle-aged general population: The HypnoLaus study DP - 2011 Sep 01 TA - European Respiratory Journal PG - 3241 VI - 38 IP - Suppl 55 4099 - http://erj.ersjournals.com/content/38/Suppl_55/3241.short 4100 - http://erj.ersjournals.com/content/38/Suppl_55/3241.full SO - Eur Respir J2011 Sep 01; 38 AB - Introduction: Prevalence of sleep disordered breathing (SDB) in middle-aged general population was reported to be around 9% of women and 27% of men in studies performed in the 80's-90's. Considering the recent improvements in the sensitivity of recording techniques, our aim is to reevaluate the prevalence of SDB in the general population.Methods: 505 subjects (47.1% women, 50.3±5.6 y.o, BMI 25.7±4.4 kg/m2) participating in an ongoing population-based cohort study (HypnoLaus, Lausanne, Switzerland) underwent complete polysomnographic recordings at home and had an extensive clinical workup including Epworth Score (ESS). Prevalence of SDB was determined according to apnea-hypopnea index (AHI) using two different scoring criteria: AASM 1999 and 2007.Results: With AASM 2007 criteria, prevalence of SDB with AHI thresholds of 5/h, 15/h and 30/h was 45.7%, 15,7% and 6.3% respectively in men, and 19.3%,4.2% and 0.8% respectively in women. Mean ESS score was 6.9±4.2 in men and 6.4±3.8 in women. 18% of the men and 12.6% of the women had an ESS >10. The prevalence of ESS>10 and OSA with the same thresholds (5/h, 15/h, 30/h) was 6.3%, 3.4%, and 0.4% respectively in men and 2.1%, 1.3%, and 0% in women. With AASM 1999 criteria, prevalence of OSA with the same thresholds was 77.2%, 37.5% and 14.6% in men and 51.3%, 15.1% and 4.6% in women. Prevalence of OSA and ESS>10 was 12.0%, 6.7% and 2.6% in men and 5.5%, 2.1% and 0.4% in women.Conclusion: In HypnoLaus population-based study, prevalence of SDB is higher than previously reported, especially in middle-aged men. This appears to be due to differences in scoring criteria and to a higher sensitivity of nasal pressure sensors compared to thermocouple.