RT Journal Article
SR Electronic
T1 Do prognostic factors help physicians in predicting legionellosis' respiratory complications?
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p2510
VO 38
IS Suppl 55
A1 Sonia Seghezzi
A1 Marta Di Pasquale
A1 Caterina Bonino
A1 Elena Prina
A1 Stefano Aliberti
A1 Francesco Nicoli
A1 Anna Maria Brambilla
A1 Roberto Cosentini
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p2510.abstract
AB Despite prompt diagnosis and appropriate treatment against Legionella, studies reports a high incidence of complications like Acute Respiratory Distress Syndrome (ARDS). The aim of the study was to find clinical features that might identify patients at risk to develop Acute Respiratory Failure (ARF).We retrospectively investigated patients with Legionnaires disease (LD) who had been admitted to Fondazione IRCCS Ca' Granda Policlinico of Milan from January 2008 to December 2010.Thirtyseven definitive cases were found, 21 (56%) were male, 13 (35%) were Health Care Associated Pneumonia. LD was severe in 26 (70%) cases, which belonged to the highest Pneumonia Severity Index classes (IV-V). At the admission an acute respiratory failure (PaO2/FiO2 <250 or SpO2< 90% or PaO2< 60 mmHg) was found in 18 patients (48%), 4 of these met ARDS criteria and non invasive-ventilation (CPAP) was necessary in 7 (19%). There were no significant differences in demographic and clinical features between the two groups (not-ARF vs ARF), see table.View this table:Only one patient required an ICU admission and one patient died (3%). An appropriate antibiotic therapy was initiated in all patients on admission day.In conclusion, though no warning prognostic sign has been found yet, clinicians should remain vigilant about the respiratory complications in patients with Legionellosis.