@article {Brussellep3956, author = {Guy G. Brusselle and Paul Van Den Brande and Rudy Pech{\'e} and Bart Fonteyn and Domenico Iacono and Marianne Blockmans and Jacques Bruhwyler and Wim Hollanders}, title = {Real-life effectiveness of beclomethasone diproprionate/formoterol extra-fine combination in adult patients with persistent asthma}, volume = {38}, number = {Suppl 55}, elocation-id = {p3956}, year = {2011}, publisher = {European Respiratory Society}, abstract = {Background: Efficacy and safety of extra-fine beclomethasone dipropionate 100 μg/formoterol 6 μg pMDI (BDP/F) in adult patients with moderate-to-severe persistent asthma has been demonstrated in double-blind randomized controlled clinical trials.Objective: To assess real-life effectiveness of BDP/F on asthma control.Methods: Non-interventional, prospective, open-label, multicentre study in Belgium from December 2008 till December 2010. Patients were enrolled by pneumologists and general practitioners (GPs). Visit 1 (Day 0): demographic and baseline asthma control data collection, initiation of BDP/F treatment; Visit 2 (Day 61-240) and Visit 3 (Day 241-420): evaluation of asthma control by patients (Juniper ACQ7) and investigators (GINA asthma control score), assessment of BDP/F safety/tolerability.Results: 619 patients were enrolled: mean age 48{\textpm}16.9 years, 54\% female, 22.8\% smokers, mean FEV1\% pred 78.6{\textpm}20.0\%. At visit 3 the mean daily beclomethasone dose was 266{\textpm}127μg.View this table:Table 1. Evolution of ACQ7 and GINA asthma control scoresSimilar improvements in asthma control, evaluated as patient-reported ACQ7 score or physician-rated GINA asthma control score, were observed in patients recruited by pneumologists and by GPs. Treatment-related non-serious adverse drug reactions were reported in 16 patients (2.6\%).Conclusion: The results of this study demonstrate the real-life effectiveness of extrafine BDP/F in adult patients with moderate-to-severe persistent asthma.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/38/Suppl_55/p3956}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }